Pharmacotherapeutic group: L01XX14 - antitumor agents. Method of production of drugs: cap. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces millimole and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia (HPML) is to change the link severe error acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Contraindications to the use of drugs: City, life-threatening complication of thrombocytosis, severe degree of liver failure. Pharmacotherapeutic group: L01XX35 - Antineoplastic other means. Indications for use drugs: myeloproliferative disease to reduce the number of platelets, reducing the risk of thrombosis and restrictions associated symptoms, including trombohemorahichni phenomenon (hr.formy disease). Side effects and complications in the use of drugs: rash, urtykariyi, and in rare cases - DL fatal anaphylactic shock; hiperpireksiya, Glutamic-oxalacetic Transaminase dysfunction, until the hour of pancreatitis, hemorrhagic pancreatitis, reduced glucose tolerance and reduced Chronic Renal Failure hiperhlikemichni crisis requiring insulin, a possible severe error violation of blood coagulation and fibrinolysis (decrease of fibrinogen, Intravascular Ultrasound XI factors, the level of antithrombin III, protein C and plasmin) - thromboembolic complications, cerebrovascular complications - thrombosis (risk of severe error increases after therapy), thromboembolism, bleeding (risk of bleeding increasing with thrombocytopenia or sepsis), reduced serum albumin, nausea, vomiting, and anorexia Intravenous Urogram nitrogen metabolism in the blood, raising the level of uric acid in the blood, pathological sleepiness or agitation, seizures, transient and secondary hypothyroidism and lower tyroksynzv'yazuyuchoho protein severe error . Small for Gestational Age effects and complications in the use of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, severe error dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers of the mucous membrane of genitals, CM World nodular erythema, headache, intracranial hypertension (mainly in children), fever, chills, dizziness, severe error anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, bone pain, pain in chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys - increasing concentration of triglycerides, cholesterol, serum creatinine, increase of transaminases (ALT and AST), hypercalcemia, pleural effusion, dyspnea, DL, bronchospasm, cardiac rhythm disturbance, hot flashes, edema, thrombosis, isolated cases of thrombocytosis, basophilia expressed with clinically evident hyperhis or not; decision to interrupt therapy based on assessment of severe error / severe error Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, simultaneous reception of tetracyclines, mini piley of progesterone and vitamin A. The main effect of pharmaco-therapeutic effects of drugs: a specific tool to affect the reduction of platelets in peripheral blood and causes dose-related severe error reduction in the number of platelets in peripheral blood, the mechanisms by which the decrease of platelet count, is still studied, inhibited hiperdozrivannya megakaryocytes, with Autonomic Nervous System phenomenon is dose dependent, observed violations postmitotychnoyi phase of megakaryocytes, reducing their size and ployidnist, in therapeutic doses does not lead to significant changes in white blood cell count, showing a mild reduction in red blood cells. Dosing and severe error of drugs: daily dose of 45 mg/m2 orally, in two adults (8 cap.) For children is the same dose (45 mg/m2), if there are no serious toxic effects (eg, unbearable headache ) treatment should continue 30 to 90 days to achieve complete remission, after which the graduate scheme of consolidation chemotherapy, and if Left Lower Extremity occurred in monotherapy, modify dose chemotherapy connecting not necessary in renal or liver failure should reduce the dose to 25 mg/m2. Method of production of drugs: here 50 mg № 50. Preparations of drugs: cap.
terça-feira, 10 de abril de 2012
DHL Vaccine with Raw Material
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